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Antibiotic resistance : Fostering innovation to solve an inevitable problem

Antimicrobial resistance (AMR) is a widely discussed topic.

  • EditeurAlcimed
  • Version PDF - 25 pages - 2023 - Anglais
Livre blanc - "Antibiotic resistance : Fostering innovation to solve an inevitable problem" - Alcimed

Introduction ou extrait du livre blanc

"The purpose of this paper is not to provide an exhaustive review of scientific literature, but rather to provide examples of innovative solutions and assess their potential to help overcome this inevitable problem. This paper focuses on antibiotic resistance, as bacteria represent the highest priority category of drug-resistant microbes.

Seventy years after the first antibiotics were used in human therapy, bacterial resistance is perceived as a growing threat to both individuals and public health. This phenomenon has mobilized scientists and physicians for more than thirty years, and more recently, administrative institutions and political power. The development of antibiotics is one of the greatest advances in medicine: thanks to these drugs, it is possible to treat serious pathologies, such as pneumonia or septicemia, which were often fatal before, or to prevent and treat infections in patients undergoing surgery or immunosuppressive treatments, such as chemotherapy.

However, due to the overuse and sometimes inappropriate use of antibiotics, an increasing number of bacteria have become resistant to their action. Antibiotic resistance is the ability of a bacterium to develop defense mechanisms that allow it to escape the action of these drugs. T

he acquisition of resistance mechanisms by bacteria has been accelerated over time, and resistance to some important groups of antibiotics, and the rise of multi-drug resistant germs are of particular concern."

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